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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GBA3
All Species:
11.82
Human Site:
S274
Identified Species:
28.89
UniProt:
Q9H227
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H227
NP_001121904.1
469
53696
S274
V
V
K
S
Q
I
A
S
M
S
Q
K
Q
G
Y
Chimpanzee
Pan troglodytes
XP_517125
469
53674
S274
V
V
K
S
Q
I
A
S
M
S
Q
K
Q
G
Y
Rhesus Macaque
Macaca mulatta
XP_001105060
469
53778
S274
V
V
K
S
Q
I
A
S
M
S
Q
K
Q
G
Y
Dog
Lupus familis
XP_545975
469
53689
F274
V
V
K
S
Q
I
A
F
M
S
K
K
Q
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1F9
566
64807
T308
V
M
K
D
H
I
G
T
K
S
A
E
Q
G
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513443
542
60826
A344
L
V
K
S
Q
V
A
A
M
S
Q
K
Q
G
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087678
499
56923
E277
S
M
K
L
K
I
S
E
N
S
K
K
E
G
L
Zebra Danio
Brachydanio rerio
NP_001018529
475
53419
L281
I
E
N
R
S
L
E
L
G
Y
K
Q
G
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792769
548
61806
A311
V
M
K
S
K
I
A
A
K
S
T
A
Q
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FIW4
490
56058
N292
M
R
Q
K
L
G
D
N
L
P
R
F
T
P
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.6
87.8
N.A.
36.7
N.A.
N.A.
67.3
N.A.
58.3
52.2
N.A.
N.A.
N.A.
N.A.
43.2
Protein Similarity:
100
99.5
98.9
94
N.A.
53
N.A.
N.A.
76.9
N.A.
73.5
69
N.A.
N.A.
N.A.
N.A.
58.9
P-Site Identity:
100
100
100
86.6
N.A.
40
N.A.
N.A.
73.3
N.A.
33.3
0
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
100
100
93.3
N.A.
60
N.A.
N.A.
93.3
N.A.
66.6
26.6
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
60
20
0
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
10
10
0
0
0
10
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
10
% F
% Gly:
0
0
0
0
0
10
10
0
10
0
0
0
10
80
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
70
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
80
10
20
0
0
0
20
0
30
60
0
0
0
% K
% Leu:
10
0
0
10
10
10
0
10
10
0
0
0
0
0
30
% L
% Met:
10
30
0
0
0
0
0
0
50
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% P
% Gln:
0
0
10
0
50
0
0
0
0
0
40
10
70
0
0
% Q
% Arg:
0
10
0
10
0
0
0
0
0
0
10
0
0
0
10
% R
% Ser:
10
0
0
60
10
0
10
30
0
80
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
10
0
10
0
0
% T
% Val:
60
50
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
40
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _